Publications
1 / A quantitative spatial cell-cell colocalizations framework enabling comparisons between in vitro assembloids and pathological specimens
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2025
Bouchard, G., Zhang, W., Ilerten, I. et al. A quantitative spatial cell-cell colocalizations framework enabling comparisons between in vitro assembloids and pathological specimens. Nat Commun 16, 1392 (2025). https://doi.org/10.1038/s41467-024-55129-6
3 / A human lung tumor microenvironment interactome identifies clinically relevant cell-type cross-talk
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2020
Gentles AJ, Hui AB, Feng W, Azizi A, Nair RV, Bouchard G, Knowles DA, Yu A, Jeong Y, Bejnood A, Forgó E, Varma S, Xu Y, Kuong A, Nair VS, West R, van de Rijn M, Hoang CD, Diehn M, Plevritis SK. A human lung tumor microenvironment interactome identifies clinically relevant cell-type cross-talk. Genome Biol. 2020 May 7;21(1):107. doi: 10.1186/s13059-020-02019-x. PubMed PMID: 32381040; PubMed Central PMCID: PMC7206807.
5 / GFPT2-Expressing Cancer-Associated Fibroblasts Mediate Metabolic Reprogramming in Human Lung Adenocarcinoma
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2018
Zhang W, Bouchard G, Yu A, Shafiq M, Jamali M, Shrager JB, Ayers K, Bakr S, Gentles AJ, Diehn M, Quon A, West RB, Nair V, van de Rijn M, Napel S, Plevritis SK. GFPT2-Expressing Cancer-Associated Fibroblasts Mediate Metabolic Reprogramming in Human Lung Adenocarcinoma. Cancer Res. 2018 Jul 1;78(13):3445-3457. doi: 10.1158/0008-5472.CAN-17-2928. Epub 2018 May 14. PubMed PMID: 29760045; PubMed Central PMCID: PMC6030462.
7 / Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model
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2017
Bouchard G, Therriault H, Geha S, Bujold R, Saucier C, Paquette B. Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model. Br J Cancer. 2017 Feb 14;116(4):479-488. doi: 10.1038/bjc.2016.448. Epub 2017 Jan 19. PubMed PMID: 28103615; PubMed Central PMCID: PMC5318978.
9 / Pre-irradiation of mouse mammary gland stimulates cancer cell migration and development of lung metastases
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2013
Bouchard G, Bouvette G, Therriault H, Bujold R, Saucier C, Paquette B. Pre-irradiation of mouse mammary gland stimulates cancer cell migration and development of lung metastases. Br J Cancer. 2013 Oct 1;109(7):1829-38. doi: 10.1038/bjc.2013.502. Epub 2013 Sep 3. PubMed PMID: 24002607; PubMed Central PMCID: PMC3790160.
2 / Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4-pRB Axis in Fibroblasts at the Invasive Tumor Edge
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2022
Bouchard G, Garcia-Marques FJ, Karacosta LG, Zhang W, Bermudez A, Riley NM, Varma S, Mehl LC, Benson JA, Shrager JB, Bertozzi CR, Pitteri SJ, Giaccia AJ, Plevritis SK. Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4-pRB Axis in Fibroblasts at the Invasive Tumor Edge. Cancer Res. 2022 Feb 15;82(4):648-664. doi: 10.1158/0008-5472.CAN-21-1705. PubMed PMID: 34853070; PubMed Central PMCID: PMC9075699.
4 / Sparse discriminative latent characteristics for predicting cancer drug sensitivity from genomic features
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2019
Knowles DA, Bouchard G, Plevritis S. Sparse discriminative latent characteristics for predicting cancer drug sensitivity from genomic features. PLoS Comput Biol. 2019 May;15(5):e1006743. doi: 10.1371/journal.pcbi.1006743. eCollection 2019 May. PubMed PMID: 31136571; PubMed Central PMCID: PMC6555538.
6 / Induction of interleukin-1β by mouse mammary tumor irradiation promotes triple negative breast cancer cells invasion and metastasis development
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2017
Bouchard G, Therriault H, Bujold R, Saucier C, Paquette B. Induction of interleukin-1β by mouse mammary tumor irradiation promotes triple negative breast cancer cells invasion and metastasis development. Int J Radiat Biol. 2017 May;93(5):507-516. doi: 10.1080/09553002.2017.1270471. Epub 2017 Jan 17. PubMed PMID: 27935337.
8 / Stimulation of triple negative breast cancer cell migration and metastases formation is prevented by chloroquine in a pre-irradiated mouse model
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2016
Bouchard G, Therriault H, Geha S, Bérubé-Lauzière Y, Bujold R, Saucier C, Paquette B. Stimulation of triple negative breast cancer cell migration and metastases formation is prevented by chloroquine in a pre-irradiated mouse model. BMC Cancer. 2016 Jun 10;16:361. doi: 10.1186/s12885-016-2393-z. PubMed PMID: 27282478; PubMed Central PMCID: PMC4901430.